Searchable abstracts of presentations at key conferences in endocrinology

ea0007s32 | Joint BES and EFES symposium: Neuroactive steroids: implications for disease and healthy ageing | BES2004

Glial cells as mediators of the neuroprotective effects of oestrogen in the central nervous system

Garcia-Segura L , Veiga S , Mendez P , Garcia-Ovejero D , DonCarlos L , Azcoitia I

Endogenous as well as exogenous androgens and oestrogen have neuroprotective properties. Oestrogen is formed locally in neural tissue from precursor androgens. In the brain, the expression of aromatase, the enzyme that catalyses the conversion of androgens to oestrogen, is restricted, under normal circumstances, to specific neuronal populations involved in neuroendocrine control and in the modulation of reproductive or sexually dimorphic behaviours. However, the expression of ...

ea0029p765 | Endocrine Disruptors | ICEECE2012

Changes of hemostatic variables during cross-sex hormone treatment in transsexual people.

Sanchez-Pacheco M. , Mijares-Zamuner M. , Negueruela-Avellan G. , Segura L. , Marco P. , Pico-Alfonso A. , Moreno-Perez O.

Introduction: Cross-sex hormone treatment (CHT) in male-to-female (M2F) transsexuals affects the hemostatic balance, with the emergence of a prothrombotic state with the use of certain estrogen (oral ethinyl estradiol vs 17β estradiol). Testosterone administration to F2M transsexuals had an antithrombotic effect. In female-to-male in (F2M) transsexuals administration of testosterone seems to carry a mild antithrombotic effect.Objective: To quantify ...